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J Anxiety Disord. 2010 Jun;24(5):452-60. doi: 10.1016/j.janxdis.2010.03.001. Epub 2010 Mar 12.

Antisocial personality disorder and anxiety disorder: a diagnostic variant?

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  • 1Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Wolfson Institute of Preventive Medicine, Centre for Psychiatry, Forensic Psychiatry Research Unit, London EC1A 7BE, UK.


Antisocial personality disorder (ASPD) with co-morbid anxiety disorder may be a variant of ASPD with different etiology and treatment requirements. We investigated diagnostic co-morbidity, ASPD criteria, and anxiety/affective symptoms of ASPD/anxiety disorder. Weighted analyses were carried out using survey data from a representative British household sample. ASPD/anxiety disorder demonstrated differing patterns of antisocial criteria, co-morbidity with clinical syndromes, psychotic symptoms, and other personality disorders compared to ASPD alone. ASPD criteria demonstrated specific associations with CIS-R scores of anxiety and affective symptoms. Findings suggest ASPD/anxiety disorder is a variant of ASPD, determined by symptoms of anxiety. Although co-morbid anxiety and affective symptoms are the same as in anxiety disorder alone, associations with psychotic symptoms require further investigation.

Copyright 2010 Elsevier Ltd. All rights reserved.

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