Send to:

Choose Destination
See comment in PubMed Commons below
Fertil Steril. 2010 Dec;94(7):2507-13. doi: 10.1016/j.fertnstert.2010.02.037. Epub 2010 Apr 7.

Oocyte maturation failure: a syndrome of bad eggs.

Author information

  • 1Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.


To show that disruption of meiotic competence results in cell cycle arrest, and the production of immature oocytes that are not capable of fertilization. Through an extensive review of animal studies and clinical case reports, we define the syndrome of oocyte maturation failure as a distinct oocyte disorder, present a classification system based on clinical parameters, and discuss the potential molecular origins for the disease.

Copyright © 2010 American Society for Reproductive Medicine. All rights reserved.

[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Write to the Help Desk