J Am Geriatr Soc. 1991 Jun;39(6):581-3.

Mania in the elderly: a 5-7 year follow-up.

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Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Abstract

A 5-7 year follow-up study of elderly individuals hospitalized on an acute psychiatric inpatient service for bipolar disorder, manic phase, demonstrates that the prognosis of mania has improved in the past 30 years. A majority of those hospitalized for mania are alive and living independently 5 years after hospitalization. However, eight of 25 (32%) patients have experienced a decline in Mini-Mental State Exam score to below 24, suggesting a clinically significant cognitive disorder. Mortality rates were higher in the manic group than expected from population norms. Compared to a group of similarly aged individuals hospitalized for unipolar depression, patients with bipolar disorder had an earlier age of onset and a lesser likelihood of being rehospitalized.

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