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Semin Respir Crit Care Med. 2010 Apr;31(2):108-14. doi: 10.1055/s-0030-1249107. Epub 2010 Mar 30.

The impact of the lung allocation score.

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  • 1Department of Pulmonary and Critical Care Medicine, University of Chicago Medical Center, Chicago, Illinois 60637, USA.


The lung allocation score (LAS) was developed in an effort to facilitate lung transplantation to more urgent and ill patients, to decrease wait time, and to change the allocation process to a more merit-based system. Four years after the implementation of the LAS, we now evaluate the impact and outcomes of this system. We have found that registrations on the wait list as well as wait time have decreased. Mortality on the wait list has decreased. There has been significant change in the distribution of diagnoses receiving transplantation with no significant difference in survival in most areas. Patients with higher LAS scores have increased short-term mortality. The LAS has affected the allocation process as well as significant outcomes in the transplant patient population.

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