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Nat Genet. 2010 Apr;42(4):282-4. doi: 10.1038/ng0410-282.

Epigenetic marks identify functional elements.

Abstract

Enhancers and transcription factor binding sites that control cell-specific transcription in higher eukaryotes can be found up to hundreds of kilobases from the promoters that they control, making their identification challenging. A new study uses a model based on histone modifications and chromatin dynamics to predict functional elements involved in androgen receptor response.

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PMID:
20348962
[PubMed - indexed for MEDLINE]
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