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J Bacteriol. 2010 May;192(10):2645-6. doi: 10.1128/JB.00159-10. Epub 2010 Mar 26.

Complete genome sequence and annotation of the Treponema pallidum subsp. pallidum Chicago strain.

Author information

  • 1Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington 98195, USA. giacal@u.washington.edu

Abstract

In syphilis research, the Nichols strain of Treponema pallidum, isolated in 1912, has been the most widely studied. Recently, important differences among T. pallidum strains emerged; therefore, we sequenced and annotated the Chicago strain genome to facilitate and encourage the use of this strain in studying the pathogenesis of syphilis.

PMID:
20348263
[PubMed - indexed for MEDLINE]
PMCID:
PMC2863575
Free PMC Article
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