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Cardiol Young. 2010 Apr;20(2):115-23. doi: 10.1017/S1047951110000181. Epub 2010 Mar 29.

Changing concepts of endocardial fibroelastosis.

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  • Department of Pediatrics, Albany Medical College, 334 State Street, Albany, NY 12210, USA. plurie1@verizon.net


Endocardial fibroelastosis is not a disease but a reaction of the endocardium. I review the history of the term with emphasis on the gradual understanding of the many causes of this reaction. I include a comprehensive list of diseases or other cardiac stresses that authors have reported in association, and I try to explain the mechanism of the reaction. Although endocardial fibroelastosis is rare today, I issue a warning of a possible epidemic recrudescence of some of the associated diseases. My hope is for nosologic purity, therefore that outworn but surviving concepts will be firmly rejected.

[PubMed - indexed for MEDLINE]
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