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Br Dent J. 2010 May 22;208(10):E20. doi: 10.1038/sj.bdj.2010.291. Epub 2010 Mar 26.

Periodontal disease might be associated even with impaired fasting glucose.

Author information

  • 1The Center for Health Promotion and Preventive Medicine, Medical Corps, Israel Defense Forces, Jerusalem, Israel. yzadik@gmail.com



To determine whether there is an association between fasting plasma glucose level and periodontal condition in a non-diabetic male population.


Data of periodic medical examinations of 815 non-diabetic male adults (mean age 38.1 + or - 7.0 years) were analysed. Blood samples were drawn from each subject following a 14-hour fast. The distance between the cement-enamel-junction to alveolar bone crest was measured at inter-proximal sites on two standardised posterior bitewing radiographs.


Higher prevalence of alveolar bone loss was found among individuals with a fasting glucose level of > or = 100 mg/dL than among individuals with <100 mg/dL (p = 0.032) and among individuals with BMI > or = 25 than among individuals with BMI <25 (p = 0.025). Associations were found between bone loss prevalence and serum triglyceride levels of > or = 200mg/dL, total cholesterol level of > or = 200mg/dL and LDL-cholesterol level of > or = 130 mg/dL (p = 0.010, p <0.001, p = 0.009, respectively).


In the studied non-diabetic adult population, periodontal disease was associated with impaired glucose level. Periodontal disease could serve as a predictor for future diabetes mellitus, or play a possible role in the glucose imbalance and diabetes mellitus development.

[PubMed - indexed for MEDLINE]
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