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J Biomed Discov Collab. 2010 Jan 25;5:1-6.

MLTrends: Graphing MEDLINE term usage over time.

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  • 1Ottawa Hospital Research Institute.


The MEDLINE database of medical literature is routinely used by researchers and doctors to find articles pertaining to their area of interest. Insight into historical changes in research areas may be gained by chronological analysis of the 18 million records currently in the database, however such analysis is generally complex and time consuming. The authors' MLTrends web application graphs term usage in MEDLINE over time, allowing the determination of emergence dates for biomedical terms and historical variations in term usage intensity. MLTrends may be used at:

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