Genomics. 1991 Mar;9(3):551-4.

The nucleotide sequence of a CpG island demonstrates the presence of the first exon of the gene encoding the human lysosomal membrane protein lamp2 and assigns the gene to Xq24.

Manoni M, Tribioli C, Lazzari B, DeBellis G, Patrosso C, Pergolizzi R, Pellegrini M, Maestrini E, Rivella S, Vezzoni P, et al.

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Istituto di Tecnologie Biomediche Avanzate, CNR, Milan, Italy.

Abstract

An EagI-EcoRI clone of human genomic DNA, p2-7, mapped to Xq24 has been sequenced. This analysis has confirmed the presence of a CpG island and has identified the first exon of the human LAMP2 gene, encoding a glycoprotein of the lysosomal membrane. Since the p2-7 clone corresponds to single-copy DNA, we can assign the human LAMP2 gene to Xq24.

PMID:: 2032724; [PubMed - indexed for MEDLINE]

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Methylation and sequence analysis around EagI sites: identification of 28 new CpG islands in XQ24-XQ28. [Nucleic Acids Res. 1992]
Methylation and sequence analysis around EagI sites: identification of 28 new CpG islands in XQ24-XQ28.
Tribioli C, Tamanini F, Patrosso C, Milanesi L, Villa A, Pergolizzi R, Maestrini E, Rivella S, Bione S, Mancini M. Nucleic Acids Res. 1992 Feb 25; 20(4):727-33.
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Probes for CpG islands on the distal long arm of the human X chromosome are clustered in Xq24 and Xq28.
Maestrini E, Rivella S, Tribioli C, Purtilo D, Rocchi M, Archidiacono N, Toniolo D. Genomics. 1990 Dec; 8(4):664-70.
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Sawada R, Jardine KA, Fukuda M. J Biol Chem. 1993 Apr 25; 268(12):9014-22.
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CpG islands of the X chromosome are gene associated.
Alcalay M, Toniolo D. Nucleic Acids Res. 1988 Oct 25; 16(20):9527-43.
Review Lysosomal membrane glycoproteins. Structure, biosynthesis, and intracellular trafficking. [J Biol Chem. 1991]
Review Lysosomal membrane glycoproteins. Structure, biosynthesis, and intracellular trafficking.
Fukuda M. J Biol Chem. 1991 Nov 15; 266(32):21327-30.

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Cited by 2 PubMed Central articles

Methylation and sequence analysis around EagI sites: identification of 28 new CpG islands in XQ24-XQ28. [Nucleic Acids Res. 1992]
Methylation and sequence analysis around EagI sites: identification of 28 new CpG islands in XQ24-XQ28.
Tribioli C, Tamanini F, Patrosso C, Milanesi L, Villa A, Pergolizzi R, Maestrini E, Rivella S, Bione S, Mancini M. Nucleic Acids Res. 1992 Feb 25; 20(4):727-33.
Identification of novel RFLPs in the vicinity of CpG islands in Xq28: application to the analysis of the pattern of X chromosome inactivation. [Am J Hum Genet. 1992]
Identification of novel RFLPs in the vicinity of CpG islands in Xq28: application to the analysis of the pattern of X chromosome inactivation.
Maestrini E, Rivella S, Tribioli C, Rocchi M, Camerino G, Santachiara-Benerecetti S, Parolini O, Notarangelo LD, Toniolo D. Am J Hum Genet. 1992 Jan; 50(1):156-63.

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The nucleotide sequence of a CpG island demonstrates the presence of the first exon of the gene encoding the human lysosomal membrane protein lamp2 and assigns the gene to Xq24.
Genomics. 1991 Mar ;9(3):551-4.

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The nucleotide sequence of a CpG island demonstrates the presence of the first exon of the gene encoding the human lysosomal membrane protein lamp2 and assigns the gene to Xq24.

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