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J Mater Chem. 2009 Jan 1;19:4655-4672.

Multifunctional Nanoparticles as Biocompatible Targeted Probes for Human Cancer Diagnosis and Therapy.

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  • 1Institute for Lasers, Photonics and Biophotonics, Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, New York 14260-4200.

Abstract

The use of nanoparticles in biological application has been rapidly advancing toward practical applications in human cancer diagnosis and therapy. Upon linking the nanoparticles with biomolecules, they can be used to locate cancerous area as well as for traceable drug delivery with high affinity and specificity. In this review, we discuss the engineering of multifunctional nanoparticle probes and their use in bioimaging and nanomedicine.

PMID:
20305738
[PubMed]
PMCID:
PMC2841409
Free PMC Article
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