Carotid body paraganglioma manifesting as a malignant solitary mass on imaging: a case report

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Apr;109(4):e54-8. doi: 10.1016/j.tripleo.2009.12.014.

Abstract

A 58-year-old woman presented with a lump on the left side of the neck. Investigations by ultrasound-guided fine needle aspiration, magnetic resonance imaging, and positron emission tomography were all indicative of a diagnosis of a solitary malignant mass with no primary lesion identified. The patient underwent a level I-V leftside selective neck dissection. The histology results reported the mass as a carotid body paraganglioma. These are highly vascular lesions. Paragangliomas have characteristic features on the different imaging modalities; in this case they were atypical. This article reviews the main imaging modalities of paragangliomas and cytologic findings of the fine needle aspiration, which is not often performed for these cases owing to their high vascularity.

Publication types

  • Case Reports

MeSH terms

  • Biopsy, Fine-Needle
  • Carotid Body Tumor / diagnosis*
  • Chromogranins / analysis
  • Diagnosis, Differential
  • Female
  • Head and Neck Neoplasms / diagnosis*
  • Humans
  • Magnetic Resonance Imaging
  • Middle Aged
  • Neck Dissection
  • Positron-Emission Tomography
  • Radiography, Panoramic
  • Synaptophysin / analysis
  • Ultrasonography, Interventional

Substances

  • Chromogranins
  • Synaptophysin