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J Atten Disord. 2010 Nov;14(3):281-91. doi: 10.1177/1087054709356388. Epub 2010 Mar 12.

A compound herbal preparation (CHP) in the treatment of children with ADHD: a randomized controlled trial.

Author information

  • 1ADHD and Adaptation Clinic, Sheba Medical Center, Tel Hashomer, Israel.

Abstract

OBJECTIVE:

Evaluation of the efficacy of a patented, compound herbal preparation (CHP) in improving attention, cognition, and impulse control in children with ADHD.

METHOD:

DESIGN:

A randomized, double-blind, placebo-controlled trial.

SETTING:

University-affiliated tertiary medical center.

PARTICIPANTS:

120 children newly diagnosed with ADHD, meeting DSM-IV criteria.

INTERVENTION:

Random assignment to the herbal treatment group (n = 80) or control group (placebo; n = 40); 73 patients in the treatment group (91%) and 19 in the control group (48%) completed the 4-month trial.

OUTCOME MEASURE:

Test of Variables of Attention (TOVA) administered before and after the treatment period; overall score and 4 subscales.

RESULTS:

The treatment group showed substantial, statistically significant improvement in the 4 subscales and overall TOVA scores, compared with no improvement in the control group, which persisted in an intention-to-treat analysis.

CONCLUSIONS:

The well-tolerated CHP demonstrated improved attention, cognition, and impulse control in the intervention group, indicating promise for ADHD treatment in children.

PMID:
20228219
[PubMed - indexed for MEDLINE]
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