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Diagn Microbiol Infect Dis. 2010 Apr;66(4):445-8. doi: 10.1016/j.diagmicrobio.2009.11.013.

Mechanisms of carbapenem resistance among a collection of Enterobacteriaceae clinical isolates in a Texas city.

Author information

  • 1Department of Medicine, San Antonio Military Medical Center, Fort Sam Houston, Texas 78234, USA.

Abstract

Fourteen Enterobacteriaceae isolates with ertapenem MIC >2 mg/mL were analyzed to identify mechanisms of resistance. All isolates produced extended-spectrum beta-lactamase or AmpC beta-lactamase with variable, but decreased, expression of outer membrane proteins. One Enterobacter cloacae produced derepressed AmpC beta-lactamase, 1 Escherichia coli expressed plasmid-mediated AmpC beta-lactamase, and 1 E. cloacae produced a carbapenemase.

Published by Elsevier Inc.

PMID:
20226336
[PubMed - indexed for MEDLINE]
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