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Adv Chronic Kidney Dis. 2010 Mar;17(2):181-9. doi: 10.1053/j.ackd.2009.12.005.

Isolated polycystic liver disease.

Author information

  • Mayo Clinic College of Medicine, Rochester, MN 55905, USA. qian.qi@mayo.edu

Abstract

Isolated polycystic liver disease (PCLD) is an autosomal dominant disease with genetic and clinical heterogeneity. Apart from liver cysts, it exhibits few extrahepatic manifestations, and the majority of patients with this condition are asymptomatic or subclinical. However, a small fraction of these patients develop acute liver cyst-related complications and/or massive cystic liver enlargement, causing morbidity and mortality. Currently, the management for symptomatic PCLD is centered on palliating symptoms and treating complications.

2010 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

PMID:
20219621
[PubMed - indexed for MEDLINE]
PMCID:
PMC2837599
Free PMC Article

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