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    Am J Med Sci. 1991 May;301(5):337-52.

    Recent advances in the treatment of breast cancer.

    Ziegler LD, Buzdar AU.

    Source

    Department of Medicine (Medical Breast), University of Texas, M.D. Anderson Cancer Center, Houston 77030.

    Abstract

    Multidisciplinary efforts have defined a number of prognostic factors and newer strategies to improve the outcome of patients with breast cancer. Conservative surgery has led to improved functional and cosmetic results. The development of a number of effective adjuvant regimens has led to improved survival. In patients with stage I disease, several biological characteristics of tumor have been identified that are associated with increased risk of relapse. A multimodality approach to patients with locally advanced disease and inflammatory cancer has resulted in improved survival. A number of hormonal and cytotoxic drug contaminations can palliate metastatic disease, with a small fraction of patients remaining in extended remission. Dose-intensive programs may lead to further improvements in survival of selected patients with this disease.

    PMID:
    2021157
    [PubMed - indexed for MEDLINE]

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