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Cell. 2010 Mar 5;140(5):615-8. doi: 10.1016/j.cell.2010.02.030.

TB: screening for responses to a vile visitor.

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  • 1Research Institute, McGill University Health Center, Montreal, Quebec H3G 0B1, Canada.

Abstract

Mycobacteria, the pathogens that cause tuberculosis and leprosy, establish long-term infections in host macrophages. Recent studies, including two genetic screens reported in this issue of Cell (Kumar et al., 2010; Tobin et al., 2010), reveal that virulent mycobacteria evade the host immune system by stimulating production of anti-inflammatory molecules and inhibiting autophagy.

(c) 2010 Elsevier Inc. All rights reserved.

PMID:
20211131
[PubMed - indexed for MEDLINE]
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