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J Biomed Opt. 2010 Jan-Feb;15(1):016029. doi: 10.1117/1.3302806.

Doppler variance imaging for three-dimensional retina and choroid angiography.

Author information

  • 1University of California, Irvine, Irvine Beckman Laser Institute, Department of Biomedical Engineering, Irvine, California 92612, USA. yulingfeng@gmail.com

Abstract

We demonstrate the use of Doppler variance (standard deviation) imaging for 3-D in vivo angiography in the human eye. In addition to the regular optical Doppler tomography velocity and structural images, we use the variance of blood flow velocity to map the retina and choroid vessels. Variance imaging is subject to bulk motion artifacts as in phase-resolved Doppler imaging, and a histogram-based method is proposed for bulk-motion correction in variance imaging. Experiments were performed to demonstrate the effectiveness of the proposed method for 3-D vasculature imaging of human retina and choroid.

PMID:
20210473
[PubMed - indexed for MEDLINE]
PMCID:
PMC2839803
Free PMC Article

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