Format

Send to:

Choose Destination
See comment in PubMed Commons below
Vaccine. 2010 Apr 26;28(19):3488-95. doi: 10.1016/j.vaccine.2010.02.053. Epub 2010 Mar 1.

Evaluating the Brighton Collaboration case definitions, aseptic meningitis, encephalitis, myelitis, and acute disseminated encephalomyelitis, by systematic analysis of 255 clinical cases.

Author information

  • 1Charité University Medicine, Department of Pediatrics, 13553 Berlin, Germany. Barbara.Rath@gmail.com

Abstract

AIMS:

Brighton Collaboration (BC) case definitions are independent from presumed causes or triggers, hence should be applicable in routine clinical settings.

SCOPE:

255 cases with discharge diagnoses of aseptic meningitis (ASM; n=164), encephalitis (ENC; n=48), myelitis (MYE; n=8), ADEM (n=10), or bacterial meningitis (BM; n=59; control group) were tested against the BC case definitions ASM, ENC, MYE, and ADEM. Overall rates of agreement between BC criteria and discharge diagnoses were 70%, 78%, 97%, and 97% for ASM, ENC, MYE and ADEM, respectively.

CONCLUSION:

BC case definitions are easily applicable in retrospective chart reviews allowing causality assessments with minimal selection bias.

Copyright 2010 Elsevier Ltd. All rights reserved.

PMID:
20197145
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk