Nat Methods. 2010 Mar;7(3 Suppl):S16-25.

Visualization of multiple alignments, phylogenies and gene family evolution.

Procter JB, Thompson J, Letunic I, Creevey C, Jossinet F, Barton GJ.

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University of Dundee, UK. j.procter@dundee.ac.uk

Abstract

Software for visualizing sequence alignments and trees are essential tools for life scientists. In this review, we describe the major features and capabilities of a selection of stand-alone and web-based applications useful when investigating the function and evolution of a gene family. These range from simple viewers, to systems that provide sophisticated editing and analysis functions. We conclude with a discussion of the challenges that these tools now face due to the flood of next generation sequence data and the increasingly complex network of bioinformatics information sources.

PMID:: 20195253; [PubMed - indexed for MEDLINE]

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