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Ultrastruct Pathol. 2010 Apr;34(2):68-72. doi: 10.3109/01913120903506611.

Banded collagen in the kidney with special reference to collagenofibrotic glomerulopathy.

Author information

  • 1Jaslok Hospital & Research Center, Bhatia Hospital, Mumbai, India. shailakhubchandani@yahoo.co.in

Abstract

BACKGROUND:

The normal glomerular basement membrane, composed of type IV collagen, plays an important function in the process of filtration. Rarely, type III, type I, or type V collagen is seen in the glomerulus, resulting in three different types of non-immune mediated glomerulopathies recognized thus far. These are characterized by deposition of banded collagen fibers in the glomerulus.

METHODS:

The authors reviewed 4934 kidney biopsies submitted over the past 5 years. Five of these revealed the presence of banded collagen in the glomeruli.

CONCLUSION:

Combined clinical and ultrastructural examination has led to a definitive diagnosis. These diseases exhibit indolent progression and as yet do not have specific treatment.

PMID:
20192702
[PubMed - indexed for MEDLINE]
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