Nat Chem Biol. 2010 Apr;6(4):261-3. Epub 2010 Feb 28.

Symbiotic Streptomycetes provide antibiotic combination prophylaxis for wasp offspring.

Kroiss J, Kaltenpoth M, Schneider B, Schwinger MG, Hertweck C, Maddula RK, Strohm E, Svatos A.

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Research Group Mass Spectrometry, Max Planck Institute for Chemical Ecology, Jena, Germany.

Abstract

Beewolf digger wasps cultivate specific symbiotic bacteria (Streptomyces spp.) that are incorporated into the larval cocoon for protection against pathogens. We identified the molecular basis of this protective symbiosis in the natural context and demonstrate that the bacteria produce a 'cocktail' of nine antibiotic substances. The complementary action of all symbiont-produced antibiotics confers a potent antimicrobial defense for the wasp larvae that parallels the 'combination prophylaxis' known from human medicine.

PMID:: 20190763; [PubMed - indexed for MEDLINE]

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Symbiotic Streptomycetes provide antibiotic combination prophylaxis for wasp offspring.

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