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    Fertil Steril. 2010 May 15;93(8):2750-3. Epub 2010 Feb 26.

    Progesterone receptor-mediated up-regulation of transthyretin in preimplantation mouse uterus.

    Diao H, Xiao S, Cui J, Chun J, Xu Y, Ye X.

    Source

    Department of Physiology and Pharmacology, College of Veterinary Medicine, The University of Georgia, Athens, Georgia 30602, USA.

    Abstract

    Transthyretin (TTR), a carrier for thyroxine and retinol, has its messenger RNA (mRNA) expressed in the glandular endometrial epithelium and its protein detected in the glandular endometrial epithelium and the uterine lumen. TTR mRNA is dramatically up-regulated in the preimplantation mouse uterus as well as the P-treated ovariectomized mouse uterus, and in both situations the up-regulation of TTR is blocked by treatment with the P receptor antagonist RU486.

    Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

    PMID:
    20188365
    [PubMed - indexed for MEDLINE]

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