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Can Respir J. 2010 Jan-Feb;17(1):e20-2.

Sore throat progressing to embolic sepsis: a case of Lemierre's syndrome.

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  • 1Division of Respirology, Department of Intensive Medicine, Dalhousie University, Halifax, Canada. dirks.jackie@gmail.com


Lemierre's syndrome is a rare clinical syndrome defined as orophyngeal sepsis, thrombophlebitis of the internal jugular vein and septic thombo-emboli. It is typically encountered in young, immunocompetent individuals, with a mean incident age of 20 years. The organism that is most commonly associated is an anaerobic Gram-negative bacterium: Fusobacterium species. The defined treatment course is at least six weeks of antibiotics, with the role of anticoagulation being unclear. The present article documents a case of Lemierre's syndrome complicated by acute renal failure and loculated pleural effusion in an otherwise healthy 16-year-old patient.

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