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Dermatology. 2010;220(3):234-7. doi: 10.1159/000275676. Epub 2010 Feb 20.

Cutaneous sarcoidosis occurring during anti-TNF-alpha treatment: report of two cases.

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  • 1Department of Dermatology, Amiens University Medical Centre, South Hospital, Amiens, France. Florie.Dhaille @


We report two cases of cutaneous granuloma induced by anti-TNF-alpha therapy: a 47-year-old man suffering from psoriatic arthritis treated with infliximab and a 56-year-old woman treated with adalimumab for polyarticular juvenile rheumatoid arthritis. The biospies confirmed the diagnosis of a 'sarcoidosis-like' reaction. No systemic involvement was observed. Such cases of noninfectious granulomatous diseases occurring during anti-TNF-alpha therapy are becoming increasingly frequent.

2010 S. Karger AG, Basel.

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