Comment in

• Counterpoint: Activation of the intrarenal renin-angiotensin system is the dominant contributor to systemic hypertension. [J Appl Physiol. 2010]
  Counterpoint: Activation of the intrarenal renin-angiotensin system is the dominant contributor to systemic hypertension.Navar LG. J Appl Physiol. 2010 Dec; 109(6):1998-2000; discussion 2015.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Systemic hypertension--a "ratologist" point of view. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Systemic hypertension--a "ratologist" point of view.Julien C. J Appl Physiol. 2010 Dec; 109(6):2004.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system.Cowley AW Jr. J Appl Physiol. 2010 Dec; 109(6):2009-10.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Carotid stimulation studies support a prominent role for the sympathetic nervous system. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Carotid stimulation studies support a prominent role for the sympathetic nervous system.Wehrwein EA. J Appl Physiol. 2010 Dec; 109(6):2009.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Systemic hypertension--involvement of the CNS to this complex puzzle. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Systemic hypertension--involvement of the CNS to this complex puzzle.Moreira TS, Takakura AC, Antunes VR. J Appl Physiol. 2010 Dec; 109(6):2004.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. The role of the sympathetic nervous system--influences of sex and aging. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. The role of the sympathetic nervous system--influences of sex and aging.Charkoudian N, Hart EC, Barnes JN, Joyner MJ. J Appl Physiol. 2010 Dec; 109(6):2005.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system.Goldstein DS. J Appl Physiol. 2010 Dec; 109(6):2005-6.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Activation of the sympathetic nervous system is the dominant contributor to systemic hypertension. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Activation of the sympathetic nervous system is the dominant contributor to systemic hypertension.Negrao CE, Negrao MV. J Appl Physiol. 2010 Dec; 109(6):2006.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system.Cohn JN. J Appl Physiol. 2010 Dec; 109(6):2006-7.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system.Rohrwasser A. J Appl Physiol. 2010 Dec; 109(6):2007.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Dominant contributors for systemic hypertension--who leads, who follows? [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Dominant contributors for systemic hypertension--who leads, who follows?Braga VA. J Appl Physiol. 2010 Dec; 109(6):2007-8.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. The kidney is not always the target in neurogenic hypertension. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. The kidney is not always the target in neurogenic hypertension.Osborn JW, Fink GD. J Appl Physiol. 2010 Dec; 109(6):2008.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system.Zhao D. J Appl Physiol. 2010 Dec; 109(6):2010.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system.Head GA, Burke SL. J Appl Physiol. 2010 Dec; 109(6):2010.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Obesity: a common prime mover of chronic activation of the sympathetic nervous system and the renin-angiotensin system in systemic hypertension? [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Obesity: a common prime mover of chronic activation of the sympathetic nervous system and the renin-angiotensin system in systemic hypertension?Szelényi Z. J Appl Physiol. 2010 Dec; 109(6):2008-9.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Hung jury? [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Hung jury?Bie P, Damkjaer M. J Appl Physiol. 2010 Dec; 109(6):2011.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. The dominant mechanism depends on individual circumstance. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. The dominant mechanism depends on individual circumstance.Mathai ML. J Appl Physiol. 2010 Dec; 109(6):2011.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Remodeling of central sympathetic circuits precedes the development of hypertension. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Remodeling of central sympathetic circuits precedes the development of hypertension.Murphy MN. J Appl Physiol. 2010 Dec; 109(6):2011-2.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Sympathetic activation is the dominant contributor to systemic hypertension. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Sympathetic activation is the dominant contributor to systemic hypertension.Fu Q, Levine BD. J Appl Physiol. 2010 Dec; 109(6):2012.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. AT1 receptors in the kidney mediate the chronic hypertensive response to angiotensin II. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. AT1 receptors in the kidney mediate the chronic hypertensive response to angiotensin II.Crowley SD. J Appl Physiol. 2010 Dec; 109(6):2012-3.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Intrarenal angiotensin II generation as a hypertensinogenic mechanism. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Intrarenal angiotensin II generation as a hypertensinogenic mechanism.Gonzalez-Villalobos RA, Fuchs S. J Appl Physiol. 2010 Dec; 109(6):2013.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Sympathetic activation: cause or consequence of hypertension? [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Sympathetic activation: cause or consequence of hypertension?Campos RR, Bergamaschi CT. J Appl Physiol. 2010 Dec; 109(6):2013-4.
• Rebuttal from Navar. [J Appl Physiol. 2010]
  Rebuttal from Navar.Navar LG. J Appl Physiol. 2010 Dec; 109(6):2001-2.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Activated intrarenal renin-angiotensin system is correlated with high blood pressure in humans. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Activated intrarenal renin-angiotensin system is correlated with high blood pressure in humans.Kobori H, Fu Q, Crowley SD, Gonzalez-Villalobos RA, Campos RR. J Appl Physiol. 2010 Dec; 109(6):2003.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Sympathetic nervous system, plasma volume, and hypertension. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Sympathetic nervous system, plasma volume, and hypertension.Christensen NJ. J Appl Physiol. 2010 Dec; 109(6):2003.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Chronic activation of sympathetic nervous system and systemic hypertension--stress shows the way. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Chronic activation of sympathetic nervous system and systemic hypertension--stress shows the way.Fontes MA, Xavier CH. J Appl Physiol. 2010 Dec; 109(6):2004-5.
• Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. [J Appl Physiol. 2010]
  Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system.Li P. J Appl Physiol. 2010 Dec; 109(6):2008.