Psychiatry Res. 1991 Jan;36(1):45-9.

Brain MRI in obsessive-compulsive disorder.

Kellner CH, Jolley RR, Holgate RC, Austin L, Lydiard RB, Laraia M, Ballenger JC.

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Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425.

Abstract

Magnetic resonance imaging (MRI) brain scans were performed on 12 patients with obsessive-compulsive disorder and 12 healthy controls. Measurements of the area of the head of the caudate nucleus, cingulate gyrus thickness, intracaudate/frontal horn ratio, and area of the corpus callosum did not differ between the two groups. These limited data do not support the presence of a consistent gross brain structural abnormality in obsessive-compulsive disorder. Further studies using other anatomic measurements and other brain structural imaging techniques are warranted.

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Brain MRI in obsessive-compulsive disorder.

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