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Urol Int. 2010;84(1):67-72. doi: 10.1159/000273469. Epub 2010 Feb 17.

The use of the American Society of Anesthesiology Classification as a prognostic factor in patients with renal cell carcinoma.

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  • 1Service of Urology, Department of Pelvic Surgery, Hospital AC Camargo, São Paulo, Brazil. steniozequi@uol.com.br

Abstract

OBJECTIVES:

We analyzed whether the American Society of Anesthesiology (ASA) classification could be used as a prognostic factor in renal cell carcinoma.

METHODS:

ASA classification's impact on cancer-specific survival (CSS) and on overall survival in 145 patients submitted to radical or partial nephrectomy was evaluated, and was compared with clinicopathological variables.

RESULTS:

CSS was influenced by ASA in uni- and multivariate analyses. Five-year CSS was 95.7, 71.1 and 39.8% for ASA 1, ASA 2 and ASA 3, respectively (p = 0.007). The ASA classification influenced the overall survival too (p < 0.001). When 18 patients with metastases were excluded, the CSS was 95.7, 83.9 and 42.9% for ASA 1, ASA 2 and ASA 3, respectively (p = 0.001). ASA 3 patients had ten times more metastases than ASA1 patients and two times more than ASA 2 patients (p = 0.001). ASA 3 patients had fewer incidental tumors (p = 0.043) than ASA 2 and 3 patients.

CONCLUSION:

In this series, the ASA classification could be used as a prognostic factor in renal cell carcinoma.

Copyright 2010 S. Karger AG, Basel.

[PubMed - indexed for MEDLINE]
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