Genet Couns. 2009;20(4):307-15.

The velo-cardio-facial syndrome: the spectrum of psychiatric problems and cognitive deterioration at adult age.

Evers LJ, De Die-Smulders CE, Smeets EE, Clerkx MG, Curfs LM.

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Koraal Group, MFCG, Multi-Disciplinary Centre for Dual Disabilities, Heel, The Netherlands. revers@stanna.koraalgroep.nl

Abstract

The velo-cardio-facial syndrome: the spectrum of psychiatric problems and cognitive deterioration at adult age: Deletion 22q11.2 syndrome, or the velo-cardio-facial syndrome (VCFS), is a syndrome with a known but varied clinical and behavioral phenotype. We report 7 patients with 22q11.2 deletion syndrome and an intellectual disability. Aside from the described behavioral phenotype in literature, a moderate, severe or profound intellectual disability may be present. Special attention should be given to cognitive deterioration.

PMID:: 20162865; [PubMed - indexed for MEDLINE]

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The velo-cardio-facial syndrome: the spectrum of psychiatric problems and cognitive deterioration at adult age.

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