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Psychiatr Clin North Am. 2010 Mar;33(1):141-58. doi: 10.1016/j.psc.2009.11.001.

Genetics of obsessive-compulsive disorder.

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  • 1Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Johns Hopkins Hospital, Meyer 113, 600 North Wolfe Street, Baltimore, MD 21287, USA.


Obsessive-compulsive disorder is a common debilitating condition affecting individuals from childhood through adult life. There is good evidence of genetic contribution to its etiology, but environmental risk factors also are likely to be involved. The condition probably has a complex pattern of inheritance. Molecular studies have identified several potentially relevant genes, but much additional research is needed to establish definitive causes of the condition.

Copyright 2010 Elsevier Inc. All rights reserved.

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