Cancer. 1991 May 15;67(10):2653-7.

Malignant blue nevus.

Source

Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030.

Abstract

To elucidate the histologic features and biologic behavior of malignant blue nevus (MBN), 12 cases were analyzed in which the tumor showed no junctional activity and arose in a blue nevus background. Seven patients were men and five were women; their mean age was 48.8 years. Eight lesions were on the scalp, and no patient had a family history of melanoma. The histologic appearance of most lesions was a nodule or nodules of malignant cells in a blue nevus. Mitoses were present in all lesions with atypical forms in eight; however the mitotic rate exceeded two per ten high-power fields in only one lesion. Four lesions had necrosis, and four had a heavily pigmented malignant component. Four patients had recurrences; ten patients had metastases, and eight died of their disease. Therefore MBN is an aggressive neoplasm.

PMID:: 2015566; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms

Publication Types

Review

MeSH Terms

LinkOut - more resources

Medical

Supplemental Content

Save items

Related citations in PubMed

Melanoma associated with blue nevus and melanoma mimicking cellular blue nevus: a clinicopathologic study of 10 cases on the spectrum of so-called 'malignant blue nevus'. [Am J Surg Pathol. 2001]
Melanoma associated with blue nevus and melanoma mimicking cellular blue nevus: a clinicopathologic study of 10 cases on the spectrum of so-called 'malignant blue nevus'.
Granter SR, McKee PH, Calonje E, Mihm MC Jr, Busam K. Am J Surg Pathol. 2001 Mar; 25(3):316-23.
Malignant blue nevus: a report of eight cases. [J Dermatol Sci. 1992]
Malignant blue nevus: a report of eight cases.
Mehregan DA, Gibson LE, Mehregan AH. J Dermatol Sci. 1992 Nov; 4(3):185-92.
Benign and malignant cellular blue nevus. A clinicopathological study of 30 cases. [Am J Dermatopathol. 1988]
Benign and malignant cellular blue nevus. A clinicopathological study of 30 cases.
Temple-Camp CR, Saxe N, King H. Am J Dermatopathol. 1988 Aug; 10(4):289-96.
Review Malignant blue nevus. Case report and literature review. [J Am Acad Dermatol. 1988]
Review Malignant blue nevus. Case report and literature review.
Goldenhersh MA, Savin RC, Barnhill RL, Stenn KS. J Am Acad Dermatol. 1988 Oct; 19(4):712-22.
Review Malignant blue nevus. Report of four new cases and review of the literature. [Histol Histopathol. 1991]
Review Malignant blue nevus. Report of four new cases and review of the literature.
Boi S, Barbareschi M, Vigl E, Cristofolini M. Histol Histopathol. 1991 Jul; 6(3):427-34.

See reviews... See all...

Cited by 2 PubMed Central articles

A malignant melanoma associated with a blue nevus of the lip. [Ann Dermatol. 2010]
A malignant melanoma associated with a blue nevus of the lip.
Lee HY, Na SY, Son YM, Kang HK, Baek JO, Lee JR, Roh JY. Ann Dermatol. 2010 Feb; 22(1):119-24. Epub 2010 Feb 28.
Histopathogenesis of malignant skin melanoma induced in genetically susceptible transgenic mice. [Proc Natl Acad Sci U S A. 1993]
Histopathogenesis of malignant skin melanoma induced in genetically susceptible transgenic mice.
Mintz B, Silvers WK, Klein-Szanto AJ. Proc Natl Acad Sci U S A. 1993 Oct 1; 90(19):8822-6.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Malignant blue nevus.
Malignant blue nevus.
Cancer. 1991 May 15 ;67(10):2653-7.

PubMed
[Oxidative stress and pseudoexfoliation glaucoma].
[Oxidative stress and pseudoexfoliation glaucoma].
Klin Monbl Augenheilkd. 2010 Feb ;227(2):108-13. Epub 2010 Feb 12 .

PubMed
Avemar (wheat germ extract) in cancer prevention and treatment.
Avemar (wheat germ extract) in cancer prevention and treatment.
Nutr Cancer. 2009 ;61(6):891-9.

PubMed
Review: green tea polyphenols in chemoprevention of prostate cancer: preclinical...
Review: green tea polyphenols in chemoprevention of prostate cancer: preclinical and clinical studies.
Nutr Cancer. 2009 ;61(6):836-41.

PubMed
Molecular mechanisms of green tea polyphenols.
Molecular mechanisms of green tea polyphenols.
Nutr Cancer. 2009 ;61(6):827-35.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: