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Immunity. 2010 Jan 29;32(1):11-3. doi: 10.1016/j.immuni.2010.01.001.

CD4+ T cell plasticity-Th2 cells join the crowd.

Author information

  • 1Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. jfzhu@niaid.nih.gov

Abstract

In this issue of Immunity, Hegazy et al. (2010) report that in response to lymphocytic choriomeningitis virus (LCMV) infection, fully differentiated virus-specific Th2 cells can be reprogrammed into GATA-3(+)T-bet(+) cells capable of producing both interleukin-4 and interferon-gamma.

Copyright 2010 Elsevier Inc. All rights reserved.

PMID:
20152167
[PubMed - indexed for MEDLINE]
PMCID:
PMC3494417
Free PMC Article
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