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Drug Discov Today. 2010 Apr;15(7-8):306-13. doi: 10.1016/j.drudis.2010.02.001. Epub 2010 Feb 10.

Stem cell therapies for ocular surface disease.

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  • 1North East England Stem Cell Institute, Central Parkway, Newcastle upon Tyne NE13BZ, UK.


Transparency of the cornea on the front surface of the eye is essential for vision. A variety of blinding ocular surface diseases involve the cornea. This review focusses on vision loss caused by disruption of the integrity and function of the outermost corneal layer (the epithelium) and the stem-cell-based therapeutic strategies in use and under development to restore sight in affected patients.

2010 Elsevier Ltd. All rights reserved.

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