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Clin Infect Dis. 2010 Mar 15;50(6):e38-40. doi: 10.1086/650582.

Intravenous and inhalational colistin-induced respiratory failure.

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  • 1Pharmacy Department, Harper University Hospital/Hutzel Women's Hospital, Detroit Medical Center, Wayne State University, Detroit, Michigan 48201, USA. kwahby@dmc.org


The emergence of highly resistant gram-negative pathogens in hospitals around the world has placed emphasis on colistin, a seemingly ancient drug. Respiratory failure from colistin was reported in the years following its release; however, there are no recent reports of colistin-induced respiratory failure. We report a case of intravenous colistin- and, later, inhalational colistin-induced respiratory failure.

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