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Cell. 2010 Feb 5;140(3):306-8. doi: 10.1016/j.cell.2010.01.036.

Nups take leave of the nuclear envelope to regulate transcription.

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  • 1Department of Biology, Emory University, 1510 Clifton Road, Atlanta, GA 30322, USA.

Abstract

Although components of the nuclear pore complex have been implicated in gene regulation independent of their role at the nuclear envelope, the evidence so far has been indirect. Capelson et al. (2010) and Kalverda et al. (2010) now reveal that certain nucleoporins are actively involved in transcription inside the nucleoplasm of Drosophila cells.

2010 Elsevier Inc. All rights reserved.

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PMID:
20144754
[PubMed - indexed for MEDLINE]
PMCID:
PMC3040115
Free PMC Article

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