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Curr Biol. 2010 Jan 26;20(2):R53-4. doi: 10.1016/j.cub.2009.11.058.

Convergent sequence evolution between echolocating bats and dolphins.

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  • 1School of Life Sciences, East China Normal University, Shanghai 200062, China.

Abstract

Cases of convergent evolution - where different lineages have evolved similar traits independently - are common and have proven central to our understanding of selection. Yet convincing examples of adaptive convergence at the sequence level are exceptionally rare [1]. The motor protein Prestin is expressed in mammalian outer hair cells (OHCs) and is thought to confer high frequency sensitivity and selectivity in the mammalian auditory system [2]. We previously reported that the Prestin gene has undergone sequence convergence among unrelated lineages of echolocating bat [3]. Here we report that this gene has also undergone convergent amino acid substitutions in echolocating dolphins, which group with echolocating bats in a phylogenetic tree of Prestin. Furthermore, we find evidence that these changes were driven by natural selection.

Copyright 2010 Elsevier Ltd. All rights reserved.

PMID:
20129036
[PubMed - indexed for MEDLINE]
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