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Obes Surg. 2010 Apr;20(4):506-8. doi: 10.1007/s11695-010-0074-6. Epub 2010 Feb 2.

Long-term results of gastric bypass surgery in morbidly obese type 1 diabetes patients.

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  • 1Diabetology and Metabolic Diseases Department, Barlicki University Hospital No 1, Kopcinskiego 22, Lodz, Poland. leszek.czupryniak@umed.lodz.pl

Abstract

BACKGROUND:

Long-term effects of bariatric surgery in morbidly obese type 1 patients are unknown. Five to eight-year experience in the case series of type 1 diabetes subjects is presented.

METHODS:

Three poorly controlled type 1 diabetes patients, aged 19, 23, and 28 underwent Roux-en-Y gastric bypass surgery.

RESULTS:

Their maximum body weight reduction noted during the follow-up was between 27% and 31% of baseline body weight, insulin requirement decreased from 0.6-0.95 to 0.3-0.83 IU/kg, and absolute reduction in HbA(1c) was 3-4%. Significant improvement in blood pressure, plasma lipid profile, and microalbuminuria was noted.

CONCLUSIONS:

RYGB surgery in morbidly obese type 1 diabetes patients leads to a significant and maintained weight loss and results in remarkable improvement in blood glucose control and concomitant disorders. Bariatric surgery should be recommended to significantly obese type 1 diabetes patients as a means of reduction of vascular complications risk.

[PubMed - indexed for MEDLINE]
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