Toxicity management strategy. CNS, central nervous system; EFV, efavirenz; NVP, nevirapine; SS, skin symptoms. *EFV strategy included participants who continued to receive EFV for 30 days after the initial targeted toxicity; participants may have made a subsequent switch to NVP after 30 days. **NVP strategy included participants who switched to NVP within 30 days after the initial targeted toxicity. ***Temporarily discontinued antiretroviral therapy within 4 weeks after targeted adverse event.