Abstract
An unusual rhodium carbenoid approach for introduction of 4-substituted (Z)-pent-2-enoates into sterically encumbered pyrroles and indoles is described. These studies show that (Z)-vinylcarbenoids have a greater tendency than (E)-vinylcarbenoids to react at the vinylogous position of the carbenoid rather than at the carbenoid center.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Butyrates / chemistry*
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Indoles / chemistry*
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Nitro Compounds / chemistry*
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Organometallic Compounds / chemistry*
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Pyrroles / chemistry*
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Rhodium / chemistry*
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Stereoisomerism
Substances
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6-(nitrooxy)hexyl-(2z)-4-(acetyloxy)-3-(4-(methylsulfonyl)phenyl)-2-phenylbut-2-enoate
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Butyrates
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Indoles
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Nitro Compounds
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Organometallic Compounds
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Pyrroles
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Rhodium