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Sleep. 2010 Jan;33(1):69-74.

Sleep disturbance immediately prior to trauma predicts subsequent psychiatric disorder.

Author information

  • 1University of New South Wales, Sydney, Australia. r.bryant@unsw.edu.au

Abstract

STUDY OBJECTIVES:

This study investigated the extent to which sleep disturbance in the period immediately prior to a traumatic event predicted development of subsequent psychiatric disorder.

DESIGN:

Prospective design cohort study.

SETTING:

Four major trauma hospitals across Australia.

PATIENTS:

A total of 1033 traumatically injured patients were initially assessed during hospital admission and followed up at 3 months (898) after injury.

MEASURES:

Lifetime psychiatric disorder was assessed in hospital with the Mini-International Neuropsychiatric Interview. Sleep disturbance in the 2 weeks prior to injury was also assessed using the Sleep Impairment Index. The prevalence of psychiatric disorder was assessed 3 months after traumatic injury.

RESULTS:

There were 255 (28%) patients with a psychiatric disorder at 3 months. Patients who displayed sleep disturbance prior to the injury were more likely to develop a psychiatric disorder at 3 months (odds ratio: 2.44, 95% CI: 1.62-3.69). In terms of patients who had never experienced a prior disorder (n = 324), 96 patients (30%) had a psychiatric disorder at 3 months, and these patients were more likely to develop disorder if they displayed prior sleep disturbance (odds ratio: 3.16, 95% CI: 1.59-4.75).

CONCLUSIONS:

These findings provide evidence that sleep disturbance prior to a traumatic event is a risk factor for development of posttraumatic psychiatric disorder.

PMID:
20120622
[PubMed - indexed for MEDLINE]
PMCID:
PMC2802249
Free PMC Article
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