Vaccine. 2010 Mar 16;28(13):2550-5. Epub 2010 Jan 29.

Effect of an immunization program on seasonal influenza hospitalizations in Mexican children.

Aranda-Romo S, Comas-García A, García-Sepúlveda CA, Hernández-Salinas AE, Piña-Ramírez M, Noyola DE.

Source

Microbiology Department, Facultad de Medicina, Universidad Autónoma de San Luis Potosí, Avenida Venustiano Carranza 2405, San Luis Potosí 78210, S.L.P., Mexico.

Abstract

We analyzed 2378 respiratory samples of children <5 years of age admitted during a 7-year period in order to determine the contribution of seasonal influenza as a cause of hospitalizations, as well as the impact of the inclusion of influenza vaccine in the childhood immunization program. The presence of influenza virus was demonstrated in 106 (4.4%) samples. The proportion of influenza hospitalizations after the introduction of influenza vaccination was lower (3.4%) than before the establishment of this vaccination program (7.5%; P=0.00002). Our study shows that influenza vaccination programs in children significantly reduce the impact of influenza related hospitalizations.

PMID:: 20117263; [PubMed - indexed for MEDLINE]

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Research Support, Non-U.S. Gov't

MeSH Terms

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Influenza Vaccines

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