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Emerg Infect Dis. 2010 Feb;16(2):314-7. doi: 10.3201/eid1602.091141.

Extensive mammalian ancestry of pandemic (H1N1) 2009 virus.

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  • 1Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, Tennessee 38105-3678, USA.

Abstract

We demonstrate that the novel pandemic influenza (H1N1) viruses have human virus-like receptor specificity and can no longer replicate in aquatic waterfowl, their historic natural reservoir. The biological properties of these viruses are consistent with those of their phylogenetic progenitors, indicating longstanding adaptation to mammals.

PMID:
20113569
[PubMed - indexed for MEDLINE]
PMCID:
PMC2958019
Free PMC Article

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