Knowledge of cervical cancer prevention and human papillomavirus among women with HIV

Gynecol Oncol. 2010 Apr;117(1):70-6. doi: 10.1016/j.ygyno.2009.12.030. Epub 2010 Jan 27.

Abstract

Objective: To assess knowledge of and attitudes towards human papillomavirus (HPV), Pap testing, and the HPV vaccine.

Methods: In a multicenter U.S. cohort study, women with the human immunodeficiency virus (HIV) and at-risk comparison women completed 44-item standardized self-report questionnaires exploring their knowledge of cervical cancer prevention, HPV, and HPV vaccination. Results were correlated with demographic variables, measures of education and attention, and medical factors. Data were clustered using principal component analysis. Significant associations were assessed in multivariable models.

Results: Among 1588 women, HIV seropositive women better understood facts about cervical cancer prevention and HPV than seronegative women, but both had substantial knowledge deficits. Almost all women considered Pap testing important, although 53% of HIV seropositive and 48% of seronegative women considered cervical cancer not preventable (P=0.21). Only 44% of HIV seropositive women knew Paps assess the cervix, versus 42% of HIV seronegative women (P=0.57). Both groups understood that HPV causes genital warts and cervical cancer (67% of HIV seropositive vs. 55% of seronegative women, P=0.002). About half of both groups considered HPV vaccination extremely important for cervical cancer prevention. HIV seronegative women were more likely to report learning of HPV vaccination through advertising than from clinicians (81% vs. 64%, P<0.0001).

Conclusion: High risk women need effective education about cervical cancer prevention, HPV, and HPV vaccination.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Cohort Studies
  • Female
  • HIV Infections / complications*
  • HIV Infections / psychology
  • HIV Infections / virology
  • Health Knowledge, Attitudes, Practice*
  • Humans
  • Middle Aged
  • Papillomavirus Infections / complications*
  • Papillomavirus Infections / psychology
  • Papillomavirus Infections / virology
  • Papillomavirus Vaccines / administration & dosage
  • Patient Education as Topic
  • Uterine Cervical Neoplasms / prevention & control*
  • Uterine Cervical Neoplasms / psychology
  • Uterine Cervical Neoplasms / virology*

Substances

  • Papillomavirus Vaccines