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Physiol Behav. 2010 Jun 1;100(3):250-4. doi: 10.1016/j.physbeh.2010.01.015. Epub 2010 Jan 25.

Regulatory long non-coding RNAs and neuronal disorders.

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  • 1Developmental Biology and Department of Pediatrics, Children's Memorial Hospital and Feinberg School of Medicine, Northwestern University, Box 204, 2430 N. Halsted, Chicago, IL 60614, United States. j-kohtz@northwestern.edu

Abstract

Increasing evidence suggests that GABA neuropathies play a major role in a variety of neuronal disorders. In addition, the role of non-coding RNAs in regulating a wide range of cellular processes is an intense area of investigation. This commentary discusses the intersection of these two fields, a corollary to the finding that adult hippocampal GABAergic interneuron development is controlled by an embryonic non-coding RNA during development.

Copyright 2010 Elsevier Inc. All rights reserved.

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