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Genome Biol. 2010 Jan 20;11(1):R6. doi: 10.1186/gb-2010-11-1-r6.

PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes.

Author information

  • 1Institute for Bioinformatics and Systems Biology (MIPS), Helmholtz Center Munich - German Research Center for Environmental Health (GmbH), Ingolst├Ądter Landstrasse 1, D-85764 Neuherberg, Germany. andreas.ruepp@helmholtz-muenchen.de

Abstract

In recent years, microRNAs have been shown to play important roles in physiological as well as malignant processes. The PhenomiR database http://mips.helmholtz-muenchen.de/phenomir provides data from 542 studies that investigate deregulation of microRNA expression in diseases and biological processes as a systematic, manually curated resource. Using the PhenomiR dataset, we could demonstrate that, depending on disease type, independent information from cell culture studies contrasts with conclusions drawn from patient studies.

PMID:
20089154
[PubMed - indexed for MEDLINE]
PMCID:
PMC2847718
Free PMC Article

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