Source
Advanced Pelvic Surgery and Urogynecology, Atlanta Urogynecology Associates, Atlanta, GA 30005, USA. moorer33@hotmail.com
Abstract
INTRODUCTION AND HYPOTHESIS:
Two-year outcomes of treating cystocele with a polypropylene mesh (Perigee System with IntePro, AMS, Inc.) placed via a transobturator approach are reported.
METHODS:
A prospective, multicenter trial was conducted evaluating 114 women with >or= stage II anterior wall prolapse defined using International Continence Society guidelines. Treatment success was defined as anterior stage <or= I at a 24-month follow-up. Quality of life questionnaires were administered at baseline and follow-up. Complications were reported via adverse events.
RESULTS:
Efficacy at 24 months was 88.5% (77/87). Pelvic floor distress inventory, pelvic floor impact questionnaire-7, and pelvic organ prolapse/urinary incontinence sexual questionnaire were all significantly improved from baseline (p < 0.001). Complication rates reported were vaginal mesh extrusion 10.5% (12/114) and groin, pelvic, or vaginal pain 4.4% (5/114). Six subjects reported de novo dyspareunia. Out of the 49 subjects reporting dyspareunia at baseline, 15 were resolved postoperatively.
CONCLUSIONS:
The Perigee System is an effective treatment to repair anterior wall prolapse with a low rate of complications through a 2-year follow-up.