Neurology. 1977 Nov;27(11):1053-6.

Effect of hematin in porphyric neuropathy.

Bosch EP, Pierach CA, Bossenmaier I, Cardinal R, Thorson M.

Abstract

Early, intravenous administration of hematin in a patient with acute intermittent porphyria and severe quadriparesis may have produced partial but remarkable improvement of neuropathy, and resulted in simultaneous decline of porphyrin precursors in the blood. Intermittent, biweekly hematin infusions given 1 month after the onset of the porphyric relapse had no effect on recovery of the residual neuropathy. We believe hematin may be effective in the treatment of porphyric neuropathy, if administered before irreversible neuronal damage has occured.

PMID:: 200860; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Case Reports

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Ovid Technologies, Inc.

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Medical

Supplemental Content

Save items

Related citations in PubMed

Hematin treatment of acute porphyria. Early remission of an almost fatal relapse. [JAMA. 1976]
Hematin treatment of acute porphyria. Early remission of an almost fatal relapse.
Peterson A, Bossenmaier I, Cardinal R, Watson CJ. JAMA. 1976 Feb 2; 235(5):520-2.
Hematin therapy in porphyric attacks. [Klin Wochenschr. 1980]
Hematin therapy in porphyric attacks.
Pierach CA, Bossenmaier I, Cardinal R, Weimer M, Watson CJ. Klin Wochenschr. 1980 Aug 15; 58(16):829-32.
[Hematin treatment of porphyric neuropathy]. [Rev Iber Endocrinol. 1976]
[Hematin treatment of porphyric neuropathy].
Navarro F, Herrerías JM, Pérez Cano R, Araquistain JM, Garrido Peralta M. Rev Iber Endocrinol. 1976 Nov-Dec; 23(138):571-82.
Review Hematin therapy for the porphyric attack. [Semin Liver Dis. 1982]
Review Hematin therapy for the porphyric attack.
Pierach CA. Semin Liver Dis. 1982 May; 2(2):125-31.
Review [Hematin in the treatment of acute hepatic porphyrias]. [Internist (Berl). 1979]
Review [Hematin in the treatment of acute hepatic porphyrias].
Thier W. Internist (Berl). 1979 Sep; 20(9):454-5.

See reviews... See all...

Cited by 2 PubMed Central articles

Peripheral neuropathy in chronic occupational inorganic lead exposure: a clinical and electrophysiological study. [J Neurol Neurosurg Psychiatry....]
Peripheral neuropathy in chronic occupational inorganic lead exposure: a clinical and electrophysiological study.
Rubens O, Logina I, Kravale I, Eglîte M, Donaghy M. J Neurol Neurosurg Psychiatry. 2001 Aug; 71(2):200-4.
Treatment of peripheral neuropathies. [J Neurol Neurosurg Psychiatry....]
Treatment of peripheral neuropathies.
Hallett M, Tandon D, Berardelli A. J Neurol Neurosurg Psychiatry. 1985 Dec; 48(12):1193-207.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Gene (OMIM)
Gene records associated with Online Mendelian Inheritance in Man (OMIM) records that cite the current articles in their reference lists.
Nucleotide (Weighted)
Nucleotide records associated with the current articles through the Gene database. These are the related sequences on the Gene record that are added manually by NCBI.
OMIM (calculated)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as references in the light bulb links within or in the citations at the end of the OMIM record. The references available through the light bulb link are collected using the PubMed related articles algorithm to identify records with similar terminology to the OMIM record.
OMIM (cited)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as reference cited at the end of the OMIM record.
Protein (Weighted)
Protein records associated with the current articles through related Gene database records. These are the related sequences on the Gene record that are added manually by NCBI.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Effect of hematin in porphyric neuropathy.
Effect of hematin in porphyric neuropathy.
Neurology. 1977 Nov ;27(11):1053-6.

PubMed
Home based versus centre based cardiac rehabilitation: Cochrane systematic revie...
Home based versus centre based cardiac rehabilitation: Cochrane systematic review and meta-analysis.
BMJ. 2010 Jan 19 ;340:b5631. doi: 10.1136/bmj.b5631.

PubMed
Donor dopamine pretreatment and graft function after kidney transplantation.
Donor dopamine pretreatment and graft function after kidney transplantation.
JAMA. 2010 Jan 20 ;303(3):230; author reply 231-2.

PubMed
Mumps vaccine associated orchitis: Evidence supporting a potential immune-mediat...
Mumps vaccine associated orchitis: Evidence supporting a potential immune-mediated mechanism.
Vaccine. 2010 Mar 19 ;28(14):2671-3. Epub 2010 Jan 17 .

PubMed
Repeated restraint-induced modulation of long-term potentiation in the dentate g...
Repeated restraint-induced modulation of long-term potentiation in the dentate gyrus of the mouse.
Brain Res. 2010 Mar 12 ;1320:28-33. Epub 2010 Jan 18 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: