Vaccine. 2010 Mar 19;28(14):2671-3. Epub 2010 Jan 17.

Mumps vaccine associated orchitis: Evidence supporting a potential immune-mediated mechanism.

Clifford V, Wadsley J, Jenner B, Buttery JP.

Source

Infectious Diseases Unit, Department of General Medicine & Murdoch Childrens Research Institute, Royal Children's Hospital Melbourne, Parkville, Victoria 3052, Australia. vanessa.clifford@rch.org.au

Abstract

We report 3 cases of orchitis following vaccination with mumps-measles-rubella (MMR) vaccine, two with an onset within 3 days following vaccination. Orchitis is a common complication of mumps infection, particularly in post-pubertal males, and is also recognized as a very rare complication of mumps vaccination. These cases, discussed together with a comprehensive review of the existing literature regarding post-vaccine orchitis, highlight uncertainty regarding the pathogenesis of post-vaccine orchitis.

PMID:: 20085834; [PubMed - indexed for MEDLINE]

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Measles-Mumps-Rubella Vaccine

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