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    Results: 5

    1.

    The TRC8 ubiquitin ligase is sterol regulated and interacts with lipid and protein biosynthetic pathways.

    Lee JP, Brauweiler A, Rudolph M, Hooper JE, Drabkin HA, Gemmill RM.

    Mol Cancer Res. 2010 Jan;8(1):93-106. Epub 2010 Jan 12.

    PMID:
    20068067
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Regulated endoplasmic reticulum-associated degradation of a polytopic protein: p97 recruits proteasomes to Insig-1 before extraction from membranes.

    Ikeda Y, Demartino GN, Brown MS, Lee JN, Goldstein JL, Ye J.

    J Biol Chem. 2009 Dec 11;284(50):34889-900. Epub 2009 Oct 8.

    PMID:
    19815544
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    Dislocation of HMG-CoA reductase and Insig-1, two polytopic endoplasmic reticulum proteins, en route to proteasomal degradation.

    Leichner GS, Avner R, Harats D, Roitelman J.

    Mol Biol Cell. 2009 Jul;20(14):3330-41. Epub 2009 May 20.

    PMID:
    19458199
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78.

    Lee JN, Song B, DeBose-Boyd RA, Ye J.

    J Biol Chem. 2006 Dec 22;281(51):39308-15. Epub 2006 Oct 16.

    PMID:
    17043353
    [PubMed - indexed for MEDLINE]
    Free Article
    5.

    Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase.

    Song BL, Sever N, DeBose-Boyd RA.

    Mol Cell. 2005 Sep 16;19(6):829-40.

    PMID:
    16168377
    [PubMed - indexed for MEDLINE]

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