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    J Abnorm Psychol. 1991 Feb;100(1):63-73.

    Controlled prospective study of postpartum mood disorders: psychological, environmental, and hormonal variables.

    O'Hara MW, Schlechte JA, Lewis DA, Varner MW.

    Source

    Department of Psychology, University of Iowa, Iowa City 52242.

    Abstract

    Demographic, psychiatric, social, cognitive, and life stress variables were used to determine the etiology of depression in childbearing (CB; n = 182) and nonchildbearing (NCB; n = 179) women. Hormonal variables in postpartum depression were also evaluated. In the CB group predictors of depression diagnosis were previous depression, depression during pregnancy, and a Vulnerability (V) x Life Stress (LS) interaction; predictors of depressive symptomatology were previous depression, depressive symptoms during pregnancy, life events, and V x LS. Only estradiol was associated with postpartum depression diagnosis. In the NCB group V X LS was the only predictor of depression diagnosis; depressive symptoms during pregnancy and life events were predictors of depressive symptomatology. Previous findings about depression vulnerability were replicated. The significant V x LS interactions support the vulnerability-stress model of postpartum depression.

    PMID:
    2005273
    [PubMed - indexed for MEDLINE]

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